Keith Sonderling leads trader consensus at 42 percent as acting Labor secretary, a role he assumed in April 2026 after Lori Chavez-DeRemer resigned amid misconduct allegations and internal investigations. His prior Senate confirmation as deputy secretary, Florida Republican ties, and day-to-day oversight of department operations position him as the immediate insider favorite for permanent nomination. Bryan Slater follows at 27 percent on the strength of administration experience and policy alignment, while the 14 percent probability assigned to no announcement before year-end reflects the typical timeline for cabinet replacements and Senate HELP Committee review. Lower-priced names such as Jonathan Berry and Andrew Puzder draw support from prior Trump-era service and business backgrounds, though confirmation hurdles and competing priorities limit their near-term odds.